by Anne-Fleur | Jun 14, 2024 | News, Publications
Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease ABSTRACT Objective Improving patient selection and development of biological therapies such as vedolizumab in IBD requires a thorough understanding...
by Daisy van Schaijik | May 8, 2024 | News, Publications
Non-specific irreversible 89Zr-mAb uptake in tumours: evidence from biopsy-proven target-negative tumours using 89Zr-immuno-PET Abstract Background Distribution of mAbs into tumour tissue may occur via different processes contributing differently to the 89Zr-mAb...
by Daisy van Schaijik | May 8, 2024 | News, Publications
89Zr-Immuno-PET with Immune Checkpoint Inhibitors: Measuring Target Engagement in Healthy Organs Introduction 89Zr-immuno-PET (positron emission tomography with zirconium-89-labeled monoclonal antibodies ([89Zr]Zr-mAbs)) can be used to study the biodistribution of...
by Anne-Fleur | Apr 4, 2024 | News
Poster presentations during the EMIM 2024 in Porto During the annual European Molecular Imaging Meeting (EMIM) in Porto, nine researchers of the Immune-Image consortium presented their promising research during the poster presentations. In this article, we will give a...
by Anne-Fleur | Mar 26, 2024 | News, Publications
How to obtain the image‑derived blood concentration from 89Zr‑immuno‑PET scans ABSTRACT Background PET scans using zirconium-89 labelled monoclonal antibodies (89Zr-mAbs), known as 89Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is...
by Janneke de Haan | Jan 16, 2024 | News
An Immune-Image roundtable discussion: How can we improve an optimal patient journey of those undergoing whole body PET imaging/immune cell imaging? The Immune-Image project develops methods for visualizing the immune response before, during and after immunotherapy by...
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