by Janneke de Haan | Jun 6, 2022 | Publications
Novel PET Imaging of Inflammatory Targets and Cells for the Diagnosis and Monitoring of Giant Cell Arteritis and Polymyalgia Rheumatica ABSTRACT Introduction Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated inflammatory diseases...
by Janneke de Haan | Apr 23, 2022 | Publications
Phenotypic, transcriptomic and functional profiling reveal reduced activation thresholds of CD81 T cells in giant cell arteritis ABSTRACT Objectives Evidence from temporal artery tissue and blood suggests involvement of CD8þ T cells in the pathogenesis of GCA,...
by Janneke de Haan | Apr 23, 2022 | Publications
Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy ABSTRACT Introduction Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and molecular imaging (MI), including positron emission tomography (PET),...
by Janneke de Haan | Dec 22, 2021 | Publications
Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy ABSTRACT Introduction Radioligand theranostics (RT) in oncology use cancer-type specific biomarkers and molecular imaging (MI), including positron emission tomography (PET), single-photon...
by Janneke de Haan | Dec 7, 2021 | Publications
The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke) ABSTRACT Introduction Immunomodulatory therapies have fueled interest in targeting microglial cells as part of the...
by Janneke de Haan | Aug 31, 2021 | Publications
A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo ABSTRACT Introduction Bioorthogonal covalent labeling with self-labeling enzymes like SNAP-tag bears a high potential for specific targeting of cells for imaging...
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