by Janneke de Haan | Dec 7, 2021 | Publications
The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke) ABSTRACT Introduction Immunomodulatory therapies have fueled interest in targeting microglial cells as part of the...
by Janneke de Haan | Aug 31, 2021 | Publications
A novel 18F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo ABSTRACT Introduction Bioorthogonal covalent labeling with self-labeling enzymes like SNAP-tag bears a high potential for specific targeting of cells for imaging...
by Janneke de Haan | Feb 15, 2021 | Publications
IMPACT OF HYDROXYTYROSOL ON STROKE: TRACKING THERAPY RESPONSE ON NEUROINFLAMMATION AND CEREBROVASCULAR PARAMETERS USING PET-MR IMAGING AND ON FUNCTIONAL OUTCOMES ABSTRACT Introduction Immune cells have been implicated in influencing stroke outcomes depending on their...
by Janneke de Haan | Jan 1, 2021 | Publications
Imaging temozolomide-induced changes in the myeloid glioma microenvironment ABSTRACT Introduction The heterogeneous nature of gliomas makes the development and application of novel treatments challenging. In particular, infiltrating myeloid cells play a role in tumor...
by Janneke de Haan | Nov 1, 2020 | Publications
Characterization of the inflammatory post-ischemic tissue by full volumetric analysis of a multimodal imaging dataset ABSTRACT Introduction In vivo positron emission tomography (PET) and magnetic resonance imaging (MRI) support non-invasive assessment of the...
by Janneke de Haan | Feb 12, 2020 | Publications
TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma ABSTRACT BACKGROUND Tumor-associated microglia and macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs) are potent...
Recent Comments